FreeSurfer-Initiated Putamen, Cadate and Thalamus Segmentation in MRI Using Large Deformation Diffeomorphic Metric Mapping

PhD Student: Jingyun Chen
MSc Student: Ali Khan

We describe a new algorithm for the automated segmentation of the caudate (Caud) putamen (Put) and thalamus (Thal) in clinical Magnetic Resonance Imaging (MRI) scans. Large Deformation Diffeomorphic Metric Mapping is performed on Freesurfer-initiated templates to generate segmentation results. MR images of 24 brains (including Parkinson's diseased and Control) are used to test the algorithm. The results are compared with manual segmentations under different measurements of similarity.

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